Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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Best Choice
1
Dermeleve
Dermeleve Advanced Formula Soothing Anti-Itch Cream 120g (1 Pack)
Main highlights
- STOPS 3 TYPES OF ITCH in minutes (1) Hard to treat chronic and senior itch that has lasted 6 weeks or more (2) Itch without a rash (3) Allergic itch, such as Hives, Insect Bites & Stings, and Contact Dermatitis.
- STEROID-FREE ANTI-ITCH CREAM: Dermeleve is a next-generation OTC itchy skin relief cream formulated specifically for the most cherished of our population, the elderly. It's particularly effective for those who are 65+ with sensitive and thinning skin. Provides fast itch relief that lasts!
- SOOTHES DRY, IRRITATED SKIN with SrX-38, Ceramides, Hyaluronic Acid, and Vitamins C & E. Our steroid-free itchy skin lotion moisturizes and nourishes painful skin, promoting skin barrier repair and enhancing the skin's natural resilience against further irritation.
- NON-GREASY, RE-APPLY AS NEEDED: This gentle, yet highly effective, anti-itch lotion absorbs quickly and won't make your skin greasy. Free of fragrances corticosteroids, permethrin, formaldehyde, parabens, and skin-clogging ingredients. Hypoallergenic, non-toxic and safe for non-broken skin of all types.
- DEVELOPED & TRUSTED BY DERMATOLOGISTS across the United States. Dermeleve anti-itch cream is manufactured by Advanced Derm Solutions, a science and solutions focused company based in Tampa, Florida.
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Curious about how we select the top products for you? Explore How It Works
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
Value for Money
2
Lanacane
Lanacane Anti-Friction Gel, Soothing & Hypoallergenic Skin Moisturizer for All Skin Types, 1 oz.
Main highlights
- Non-greasy, anti-chafing gel cream dries on contact and provides long-lasting comfort
- Fragrance-free, hypoallergenic, moisture-proof, and won't stain clothes
- Anti-friction formula reduces skin rubbing on skin, skin rubbing on clothing
- Anti-Chafing Gel
- Anti chafing gel dries on contact and is moisture proof
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3
Gold Bond
Gold Bond Medicated Maximum Strength Pain & Itch Relief Cream, 1.75 oz., With Lidocaine
Main highlights
- This pain and itch formula contains 4% lidocaine, the maximum strength available without a prescription*
- This numbing cream is great for relieving pain and itch associated with sunburn, insect bites, and minor cuts, burns, and scrapes
- Includes one (1) 1.75-oz. tube of Gold Bond Medicated Maximum Strength Pain & Itch Relief Cream With Lidocaine
- Gold Bond Pain & Itch Cream with Lidocaine numbs away itching and pain due to minor skin irritations
- Gold Bond Lidocaine Cream starts working fast to relieve itching and pain associated with minor skin irritations
- Create a TerraCycle account and start recycling your empty Gold Bond packaging
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4
Gold Bond
Gold Bond Maximum Strength Medicated Anti-Itch Cream - 1 oz
Why we love it
Luxurious feel
Long lasting comfort
Rich moisturizing
Main highlights
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Key Features and Benefits
Rapid relief for irritated skin with menthol and pramoxine hydrochloride, enriched with Vitamin E and Aloe Vera, in a convenient 1 oz tube. -
Ideal Use Cases
Perfect for soothing skin irritations like scrapes, providing immediate pain relief and itch reduction in a travel-friendly size. -
Customer Reviews Highlight
Most praised for its effectiveness in quickly alleviating itch and pain, with added appreciation for its non-greasy, moisturizing formula.
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5
Cortizone 10
Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.
Why we love it
Maximum Strength: 1 hydrocortisone.
Fast acting: Relieves itch in 10 minutes.
Recommended: 1 Doctor Recommended brand.
Main highlights
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Key Features
Offers fast relief with 1% hydrocortisone for itch and inflammation from eczema, psoriasis, and more. Fragrance and dye-free with soothing aloe. -
Ideal Use Cases
Perfect for quick relief of itchiness from eczema, psoriasis, poison oak, ivy, and sumac. Effective and long-lasting for hours. -
Customer Praise
Highly praised for its quick itch relief in under 10 minutes, making it a go-to for immediate and effective treatment.
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6
HemRid
Maximum Strength Lidocaine Cream for Pain Relief. Fast-Acting Hemorrhoid Treatment Cream with 5% Lidocaine. Immediate Anal Itch Relief and Numbing
Why we love it
Maximum strength
Fast relief
Encourages shrinking
Main highlights
-
Key Features and Benefits
Maximum strength lidocaine for immediate relief from pain, itching, and discomfort of hemorrhoids without a prescription. -
Ideal Use Cases
Best for those experiencing frequent hemorrhoid flare-ups from everyday activities, needing instant and effective pain relief. -
Customer Reviews Highlight
Highly praised for its fast-acting relief, allowing users to continue daily activities with minimal discomfort.
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7
Cortizone 10
Cortizone 10 Maximum Strength Ultra Soothing Anti-Itch Cream, 1% Hydrocortisone Creme, 2 oz.
9.3 Moisturizing
9.1 worth the money
Why we love it
Maximum strength itch relief.
Fast relief of eczema, psoriasis, etc.
Non irritating, fragrance free, dye free.
Main highlights
-
Key Features
Fast itch relief with 1% hydrocortisone, 10 moisturizers plus aloe, nonirritating, fragrance and dye-free. Doctor-recommended for effective itch control. -
Ideal Use Cases
Exceptional for eczema, psoriasis, poison oak, ivy, sumac-related itches. Provides quick relief in under 10 minutes, lasting for hours. -
Customer Reviews Highlight
Most praised for its fast and effective itch relief, especially noted for conditions like eczema and psoriasis, with a gentle formula.
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8
Cortizone 10
Cortizone 10 Maximum Strength Intensive Moisture Anti-Itch Cream, 1% Hydrocortisone, 2 oz.
Main highlights
- Relieves itch in under 10 minutes and lasts for hours
- Formulated with seven moisturizers, plus vitamins A, C, and E to nourish and hydrate skin
- Features 1% hydrocortisone, the maximum-strength itch relief without a prescription
- Fast relief of itch associated with minor skin irritations like rough, dry, chafed and chapped skin
- Cortizone-10 is the #1 Doctor-Recommended OTC Anti-Itch Brand* *2021 IQVIA Study
- Cortizone-10 anti-itch cream with 24-hour moisture is gentle on skin, fragrance free and dye free
- Contains: One (1) 2-oz. tube of Cortizone-10 Maximum Strength Intensive Moisture Anti-Itch Cream
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9
Nivagen
Nivagen Maximum Strength Lidocaine 5% Anorectal Cream | Hemorrhoid Relief from Pain, Itching, Burning | 30 Gram Tube Lidocaine 5% Cream
9.1 pain management
8.0 worth the money
Why we love it
Maximum strength: 5 lidocaine
Instant relief: Pain, itching, burning
Advanced pain relief: Desensitize aggravated nerves
Main highlights
-
Key Features and Benefits
Contains maximum OTC strength 5% Lidocaine for instant pain, itching, and burning relief from hemorrhoids and anorectal disorders. -
Ideal Use Cases
Best for daily activities hindered by hemorrhoid discomfort, offering on-the-go care with its compact size for immediate symptom alleviation. -
Customer Reviews Highlight
Most praised for its quick and effective relief, allowing users to continue their routine without disruption from hemorrhoid symptoms.
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10
Aspercreme
Aspercreme with Lidocaine Maximum Strength Pain Relief Cream, 4.3 Oz
14% Off
8.4 worth the money
8.4 pain management
Why we love it
This product provides fast acting pain relief for hours.
It is a topical numbing cream that does not cause irritation or burning.
It is a fast acting Lidocaine cream that penetrates muscles and joints.
Main highlights
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Key Features
Fast-acting, odor-free cream with 4% Lidocaine for numbing pain. Non-irritating, non-greasy formula targets more pain receptors. -
Ideal Use Cases
Best for relieving minor pains associated with arthritis, backaches, muscle strains, and sprains, penetrating muscles and joints quickly. -
Customer Reviews
Highly praised for its quick pain relief and long-lasting numbness without any unpleasant odor or greasiness.
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